ELOTUZUMAB FOR THE TREATMENT OF RELAPSED OR REFRACTORY MULTIPLE MYELOMA, WITH SPECIAL REFERENCE TO ITS MODES OF ACTION AND SLAMF7 SIGNALING

ELOTUZUMAB FOR THE TREATMENT OF RELAPSED OR REFRACTORY MULTIPLE MYELOMA, WITH SPECIAL REFERENCE TO ITS MODES OF ACTION AND SLAMF7 SIGNALING

Elotuzumab, targeting signaling lymphocytic activation molecule family FERMENTED PROTEINS 7 (SLAMF7), has been approved in combination with lenalidomide and dexamethasone (ELd) for relapsed/refractory multiple myeloma (MM) based on the findings of the phase III randomized trial ELOQUENT-2 (NCT01239797).Four-year follow-up analyses of ELOQUENT-2 hav

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DETERMINE THE FINANCIAL PERFORMANCE, COMPANY SIZE, AND DIVIDEND PAYOUT RATIO ON INCOME SMOOTHING OF MANUFACTURING COMPANIES LISTED ON INDONESIA STOCK EXCHANGE

The objective of this research Tooth is to examine the impact of profitability, financial risk, company size, and Dividend Payout Ratio (DPR) on the practice of income smoothing in manufacturing companies listed on the Indonesia Stock Exchange (IDX).Purposive sampling was used to collect the sample for this study, which consisted of 25 manufacturin

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Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis

During tuberculosis (TB), migration of dendritic cells (DCs) from the site of infection to the draining lymph nodes is known to be impaired, hindering the rapid development of protective T-cell-mediated immunity.However, the mechanisms involved in the delayed migration of DCs during TB are still poorly defined.Here, we found that infection of DCs w

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